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EPILEPSY
TOPIC
SUB-TOPIC
THERAPY
TRIAL
Status epilepticus
Antiseizure medications
Levetiracetam, fosphenytoin, and sodium valproate
ECLIPSE
Levetiracetam may be a safe and effective alternative to phenytoin as a second-choice anticonvulsant in status epilepticus in children.
ECLIPSE
CONSEPT
Levetiracetam is non-superior to phenytoin as a second-choice anticonvulsant in status epilepticus in children.
CONSEPT
Focal epilepsy
Drug selection
Lamotrigine
SANAD II
Lamotrigine should remain a first-line treatment for focal epilepsy patients.
SANAD II
Temporal lobe epilepsy
Surgery
Surgery
Wiebe, 2001
Surgical management is superior to prolonged medical therapy.
Wiebe, 2001
More trials to be added in due course.
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